IFN gamma Antibody Functional Grade 16-7318-81 from Thermo Fisher Scientific

Product Specs
ItemIFN gamma Antibody Functional Grade
CompanyThermo Fisher Scientific
Price Pricing Info Supplier Page View Company Product Page
Catalog Number16-7318-81
Quantity50 µg
ApplicationsELISA, Functional assay, Neutralization
Concentration1 mg/mL
Conjugate/TagFunctional Grade
FormatPBS with no preservative; pH 7.2
ReactivityHuman
TargetIFN gamma
IsotypeIgG1 kappa
CloneNIB42
HostMouse
NCBI Full Gene Nameinterferon gamma
NCBI Gene AliasesIFG, IFI, IMD69
ClonalityMonoclonal
PurityAffinity chromatography
Storage Temperature4° C
Antibody TypePrimary
Storage4° C

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Thermo Fisher Scientific

81 Wyman Street

Waltham, MA 02451

United States

Phone: 800-678-5599
Fax: 800-331-2286

Company Profile

Website: www.thermofisher.com

(1) Contribution of Mesenchymal Stem Cells from Obese Adipose Tissue to PD-L1 Over-Expression and Breast Cancer Progression through Pathogenic Th17 Cell ActivationCancersMay 29, 2023Blangero F, Robert M, Andraud T, Dumontet C, Vidal H, Eljaafari A.(Thermo Fisher Scientific, Cat#MA5-41907, Waltham, MA, USA), anti-IFNg (Thermo Fisher Scientific, Cat#16-7318-81), or anti-TNFa (Thermo Fisher Scientific, Dardilly, France, Cat# MA5-41776) neutralizing monoclonal

(2) Interaction between PD-L1 and soluble VEGFR1 in glioblastoma-educated macrophagesBMC cancerMarch 20, 2023Liu X, Li Z, Sun J, Zhang Z, Li W.antibody (NAb) (25 µg/mL, Novus Biologicals, Cat: AF321), anti-IFN-γ NAb (10 µg/mL, eBioscience, Cat: 16-7318-81), sVEGFR1 (100 ng/mL, Biolegend, Cat: 555,802) and/or anti-PD-L1 (2 µg/mL, eBioscience, Cat: 16-5983-82)

(3) Base editing screens map mutations affecting interferon-γ signaling in cancerCancer CellFebruary 13, 2023Matthew A. Coelho, Sarah Cooper, Magdalena E. Strauss, Emre Karakoc, Shriram Bhosle, Emanuel Gonçalves, Gabriele Picco, Thomas Burgold, Chiara M. Cattaneo, Vivien Veninga, et al.Technology,Cat.#3700 FLAG,Sigma-Aldrich,Cat.#F3165 CD3,Thermo Fisher Scientific,Cat.#11-0038-42 IFNγ blocking,Thermo Fisher Scientific,Cat.#16-7318-81 CD28,Thermo Fisher Scientific,Cat.#16-0289-81 B2M,Cell Signaling Technology,Cat.#12851 MLH1,Cell

(4) Co-expression of a PD-L1-specific chimeric switch receptor augments the efficacy and persistence of CAR T cells via the CD70-CD27 axisNature communicationsOctober 13, 2022Qin L, Cui Y, Yuan T, Chen D, Zhao R, Li S, Jiang Z, Wu Q, Long Y, Wang S, et al.A2005) used at 20 μg/ml concentration. Anti-IL2 mAb (Biolegend, 500301), anti-IFN-γ mAb (ThermoFisher, 16-7318-81) and anti-CD70 mAb (Abcam, ab213102) used at 10 μg/ml concentration. Cytokine release assays CAR T cells

(5) The IGFBP3/TMEM219 pathway regulates beta cell homeostasisNature communicationsFebruary 3, 2022D'Addio F, Maestroni A, Assi E, Ben Nasr M, Amabile G, Usuelli V, Loretelli C, Bertuzzi F, Antonioli B, Cardarelli F, et al.anti-IL-1β (10 µg/ml, ThermoFisher Scientific, MA5-23691)/anti-IFN-γ (10 µg/ml, ThermoFisher Scientific, 16-7318-81), or to T1D/T2D/CTRL serum, which was added to the culturing medium in place of regular FBS (10%), for

(6) Adipose-Tissue-Derived Mesenchymal Stem Cells Mediate PD-L1 Overexpression in the White Adipose Tissue of Obese Individuals, Resulting in T Cell DysfunctionCellsOctober 3, 2021Eljaafari A, Pestel J, Le Magueresse-Battistoni B, Chanon S, Watson J, Robert M, Disse E, Vidal H.Pharma S.A.S., 92506, Rueil-Malmaison, France) at 50 μg/mL or IFNγ-neutralizing antibodies (Invitrogen, 16-7318-81) at 50 μg/mL were eventually added from the beginning of cultures. For blocking experiments, ASC/MNC

(7) ZEB1 promotes pathogenic Th1 and Th17 cell differentiation in multiple sclerosisCell reportsAugust 24, 2021Qian Y, Arellano G, Ifergan I, Lin J, Snowden C, Kim T, Thomas JJ, Law C, Guan T, Balabanov RD, et al.PeproTech), 1 μg/mL anti-IL4 (Cat# 16-7048-81, clone: MP4-25D2, eBioscience), 1 μg/mL anti-IFN-γ (Cat #16-7318-81, clone: N1B42, eBioscience). Sorting of pathogenic Th1 and Th17 cells from MS patients Fresh peripheral

(8) Induction of cytotoxic effector cells towards cholangiocellular, pancreatic, and colorectal tumor cells by activation of the immune checkpoint CD40/CD40L on dendritic cellsCancer immunology, immunotherapy : CIIMay 1, 2021Sadeghlar F, Vogt A, Mohr RU, Mahn R, van Beekum K, Kornek M, Weismüller TJ, Branchi V, Matthaei H, Toma M, et al.

(9) Fasting-induced FOXO4 blunts human CD4(+) T helper cell responsivenessNature metabolismMarch 1, 2021Han K, Singh K, Rodman MJ, Hassanzadeh S, Wu K, Nguyen A, Huffstutler RD, Seifuddin F, Dagur PK, Saxena A, et al.

(10) Allogeneic ADSCs Induce the Production of Alloreactive Memory-CD8 T Cells through HLA-ABC AntigensCellsMay 18, 2020Chang SH, Kim HJ, Park CG.

(11) Type I Interferon Therapy Limits CNS Autoimmunity by Inhibiting CXCR3-Mediated Trafficking of Pathogenic Effector T CellsCell reportsJuly 9, 2019Wang W, Chong WP, Li C, Chen Z, Wu S, Zhou H, Wan Y, Chen W, Gery I, Liu Y, et al.gamma Functional Grade Monoclonal Antibody (clone NIB42),eBioscience | Thermo Fisher Scientific,Cat# 16-7318-81 RRID:AB_469250 Human IL-4 Functional Grade Monoclonal Antibody (clone MP4–25D2),eBioscience | Thermo Fisher Scientific

(12) TNFα promotes mucosal wound repair through enhanced platelet activating factor receptor signaling in the epitheliumMucosal immunologyJuly 1, 2019Birkl D, Quiros M, García-Hernández V, Zhou DW, Brazil JC, Hilgarth R, Keeney J, Yulis M, Bruewer M, García AJ, et al.of 100 nM. Anti-TNFα, anti-IFNγ and Mouse IgG1 kappa Isotype Control (Mab1 cat 16-7348-81; NIB42 cat 16-7318-81 and P3.6.8.1 cat 14-4714-82, ThermoFisher Scientific) were used at a concentration of 10 μg/ml. p65

(13) cDNA microarray analysis identifies NR4A2 as a novel molecule involved in the pathogenesis of Sjögren's syndromeClinical and experimental immunologyOctober 1, 2017Takahashi H, Tsuboi H, Asashima H, Hirota T, Kondo Y, Moriyama M, Matsumoto I, Nakamura S, Sumida T.

(14) Interferon-γ Released by Activated CD8⁺ T Lymphocytes Impairs the Calcium Resorption Potential of Osteoclasts in Calcified Human Aortic ValvesThe American journal of pathologyJune 1, 2017Nagy E, Lei Y, Martínez-Martínez E, Body SC, Schlotter F, Creager M, Assmann A, Khabbaz K, Libby P, Hansson GK, et al.

(15) Th17 Responses to Collagen Type V, kα1-Tubulin, and Vimentin Are Present Early in Human Development and Persist Throughout LifeAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant SurgeonsApril 1, 2017Sullivan JA, Jankowska-Gan E, Hegde S, Pestrak MA, Agashe VV, Park AC, Brown ME, Kernien JF, Wilkes DS, Kaufman DB, et al.

(16) CD4 T-Cell Dysregulation in Psoriatic Arthritis Reveals a Regulatory Role for IL-22Frontiers in immunologyJanuary 1, 2017Ezeonyeji A, Baldwin H, Vukmanovic-Stejic M, Ehrenstein MR.

(17) Differential requirement for P2X7R function in IL-17 dependent vs. IL-17 independent cellular immune responsesAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant SurgeonsJuly 1, 2014Sullivan JA, Jankowska-Gan E, Shi L, Roenneburg D, Hegde S, Greenspan DS, Wilkes DS, Denlinger LC, Burlingham WJ.

(18) IFNG-mediated immune responses enhance autophagy against Mycobacterium tuberculosis antigens in patients with active tuberculosisAutophagyJanuary 1, 2014Rovetta AI, Peña D, Hernández Del Pino RE, Recalde GM, Pellegrini J, Bigi F, Musella RM, Palmero DJ, Gutierrez M, Colombo MI, et al.

(19) GATA3 up-regulation associated with surface expression of CD294/CRTH2: a unique feature of human Th cellsBloodMay 15, 2007De Fanis U, Mori F, Kurnat RJ, Lee WK, Bova M, Adkinson NF, Casolaro V.

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IFN gamma Antibody Functional Grade from Thermo Fisher Scientific

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IFN gamma Antibody Functional Grade from Thermo Fisher Scientific

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